Carbimazole-Induced Jaundice in Thyrotoxicosis: A Case Report

Carbimazole Induced Pleural Effusion: A Case Report

Objective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by the endocrinology team. Result. The patient was a 77-year-old Caucasian woman who presented with sy...

Carbimazole--resistant thyrotoxicosis.

Carbimazole (Neo-Mercazole) in Thyrotoxicosis

stressed the freedom from toxicity and potency of carbimazole as an anti-thyroid drug. Though potent, thiourea derivatives had proved to have a significant toxic risk. For this reason, most recent workers have concentrated on a comparison of carbimazole with thiourea drugs in regard to studies of toxicity. McGavack, et al. (1956), in describing their experiences in forty-one cases with special ...

Jaundice due to carbimazole.

On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase levels. Light microscopy of a liver biopsy showed increase of portal zone cellul...

Cholestatic jaundice caused by sequential carbimazole and propylthiouracil treatment for thyrotoxicosis.

A 36-year-old Chinese man presented to the Queen Mary Hospital in August 1999 with a 2-week history of jaundice due to propylthiouracil treatment for thyrotoxicosis. He had previously received carbimazole but had developed an urticarial skin rash after 2 weeks of treatment. The patient developed liver failure and fulminant pneumonitis shortly after hospital admission. Despite receiving treatmen...